Product ID:ACTINOMYCIN D FROM STREPTOMYCES SPECIES, A1410
MSDS Date:04/07/1994
FSC:6810
NIIN:00N057759
MSDS Number: BWYVG

Emergency Phone: 800-231-8327

Info Phone: 414-273-3850

Cage: 60928

Telephone: 414-273-3850

Cage: 60928

ACTINOMYCIN D; (ACTINOMYCIN D FROM STREPTOMYCES SPECIES)

CAS: 50-76-0

RTECS: AU1575000

OSHA PEL N/K

ACGIH TLV: N/K

LD50 LC50 Mixture:LD50(ORAL,RAT):7200 UG/KG
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE:MAY BE FATAL IF INHALED,
SWALLOWED OR ABSORBED THROUGH SKIN. CAUSES EYE AND SKIN IRRITATION.
MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER RESPIRATORY
TRACT. PROLONGED OR REPEATED EXPOSUR E MAY CAUSE ALLERGIC REACTIONS
IN CERTAIN SENSITIVE INDIVIDUALS. CHRONIC:MAY CAUSE CONGENITAL
MALFORM (EFTS OF OVEREXP)
Explanation of Carcinogenicity:NOT RELEVANT
Effects of Overexposure:HLTH HAZS:IN THE FETUS. POSSIBLE CARCINOGEN.
POSSIBLE MUTAGEN. TARGET ORGAN(S):BONE MARROW, LIVER, KIDNEYS. TO
THE BEST OF MFR KNOWLEDGE, THE CHEMICAL, PHYSICAL AND TOXICOLOGICAL
PROPERTIES HAVE NOT B EEN THOROUGHLY INVESTIGATED. VERY TOXICBY
INHALATION, IN CONT W/SKIN & IF SWALLOWED. IRRIT TO EYES, RESP SYS
& SKIN.
Medical Cond Aggravated by Exposure:NONE SPECIFIED BY MANUFACTURER.

First Aid:EYES:FLUSH W/COPIOUS AMTS OF WATER FOR AT LST 15 MIN. SEEK
MED ADVICE. SKIN:FLUSH WITH COPIOUS AMTS OF WATER FOR AT LST 15 MIN
WHILE REMOVING CONTAM CLOTHING AND SHOES. WASH CONTAM CLOTHING
BEFORE REU SE. INHALATION:REMOVE TO FRESH AIR. IF NOT BREATHING
GIVE ARTIFICIAL RESPIRATION. IF BREATHING IS DIFFICULT, GIVE
OXYGEN. INGESTION:WASH OUT MOUTH W/WATER PROVIDED PERSON IS
CONSCIOUS. CALL MD.

Extinguishing Media:WATER SPRAY. CARBON DIOXIDE, DRY CHEMICAL POWDER OR
APPROPRIATE FOAM.
Fire Fighting Procedures:WEAR NIOSH/MSHA APPROVED SCBA & FULL
PROTECTIVE EQUIPMENT .
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

Spill Release Procedures:WEAR NIOSH/MSHA SELF-CONTAINED BREATHING
APPARATUS, RUBBER BOOTS AND HEAVY RUBBER GLOVES. SWEEP UP, PLACE IN
A BAG AND HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST. VENTILATE
AREA AND WASH SPILL SITE A FTER MATERIAL PICKUP IS COMPLETE.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:DO NOT BREATHE DUST. DO NOT GET IN
EYES, ON SKIN, ON CLTHG. AVOID PRLNGD/RPTD EXPOS. HIGHLY TOX.
TERATOGEN. IRRITANT. POSS SENSIT. KEEP TIGHTLY CLSD.
Other Precautions:REFRIGERATE. MAY CAUSE BIRTH DEFECTS. IF YOU FEEL
UNWELL, SEEK MED ADVICE. WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES
AND EYE/FACE PROTECTION.

Respiratory Protection:WEAR APPROPRIATE NIOSH/MSHA APPROVED RESPIRATOR.
Ventilation:USE ONLY IN A CHEMICAL FUME HOOD.
Protective Gloves:CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEM WORKERS GOGGS .
Other Protective Equipment:WEAR OTHER PROTECTIVE CLOTHING. SAFETY
SHOWER AND EYE BATH.
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
NONE SPECIFIED BY MANUFACTURER.

Appearance and Odor:BRIGHT ORANGE-RED POWDER.

Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZING AGENTS, STRONG ACIDS, STRONG BASES.
Stability Condition to Avoid:NONE SPECIFIED BY MANUFACTURER.
Hazardous Decomposition Products:TOXIC FUMES OF:NITROGEN OXIDES.

Waste Disposal Methods:DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE
SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL
LAWS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.